1. In a study with 50 healthy women, Siberian ginseng significantly decreased lower limb swelling 2 and 4 hours after consumption.

2. The herb appears to reduce swelling primarily by improving lymphatic function.

3. Siberian ginseng and its component eleutheroside E activate a specific receptor (Tie2) that helps stabilize lymphatic vessels.

4. The herb enhances the connections between lymphatic endothelial cells, improving the barrier function of these vessels.

Reference:

Antiedema effects of Siberian ginseng in humans and its molecular mechanism of lymphatic vascular function in vitro

PMID: 27333960 DOI: 10.1016/j.nutres.2016.02.012